Sunday, November 27, 2016

Adrenergic drugs classification


1) Based on Structure  
a) Catecholamines
i) Natural

Adrenaline
Noradrenaline

Dopamine
ii) Synthetic

Isoprenaline
Dobutamine

b) Non Catecholamines

Ephedrine
Amphetamine
Mephentermine
Phenylephrine


2) Based on Mechanism of Action
a) Directly acting

Adrenaline
Noradrenaline
Isoprenaline
Phenylephrine
Salbutamol
Methoxamine
Xylometazoline

b) Indirectly acting
Tyramine
c) Acting by both mechanisms

Ephedrine
Amphetamine
Mephentermine


3) Based on Spectrum of Activity
a)α agonists

i) α1 selective
Phenylephrine
ii) α2 selective
Clonidine

b) β Agonists

i) Non-selective
Isoprenaline
ii) β1 selective
Dobutamine

iii) β2 selective
Terbutaline
Salbutamol

c) α and β agonists

Adrenaline
Noradrenaline

d) Dopamine agonists Dopamine (D1 and D2)
Fenoldopam

4) Clinical/ Therapeutic Classification
a) Pressor agents

Dopamine
Noradrenaline
Methoxamine
Mephentermine
Phenylephrine
Ephedrine

b) Cardiac stimulants

Adrenaline
Dobutamine
Isoprenaline

c) CNS stimulants

Amphetamine
Dexamphetamine
Methamphetamine

d) Bronchodilators

Adrenaline
Isoprenaline
Salbutamol
Salmeterol
Formoterol
Bambuterol
Fenoterol
Terbutaline
Orciprenaline
Isoetherine

e)Nasal decongestants

Naphazoline
Xylometazoline
Oxymetazoline
Phenylephrine
Pseudoephedrine
Phenylpropanolamine
Propylhexedrine

f) Uterine relaxants & vasodilators

Ritodrine
Isoxsuprine
Salbutamol
Terbutaline

g) Anorectics (appetite suppressants)

Fenfluramine
Dexfenfluramine
Sibutramine


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