Anti Parkinsonian drugs classification

1) Drugs Enhancing Dopaminergic Activity

a) Precursors of dopamine

Levodopa (l-dopa)

b) Dopaminergic agonists

Pergolide

Piribedil

Bromocriptine

Lisuride

Ropinirole

Pramipexole

Apomorphine

c) Dopamine releasing

Amantadine

d) Drugs inhibiting Dopamine metabolism

i) MAO-B Inhibitor

Selegiline

Rasagiline

ii) COMT Inhibitors

Entacapone

Tolcapone

e) Peripheral decarboxylase inhibitors

Carbidopa

Benserazide

2) Drugs Reducing Cholinergic Activity.

a)Central anti-cholinergics

Trihexyphenidyl

Procyclidine

Biperiden

Benztropine

b) Anti-histamines

Orphenadrine

Promethazine